Interstitial Cells of Cajal : Pathology , Injury and Repair = خلايا كاجال الخلالية : علم الأمراض و الإصابات و الإصلاح
نویسندگان
چکیده
منابع مشابه
Interstitial cells of Cajal - systematic review.
This paper reviews the distribution of interstitial cells of Cajal (ICC) in the human gastro-intestinal (GI) tract, based on ultrastructural and immunohistochemical evidence. The distribution and morphology of ICC at each level of the normal GI tracts is addressed from the perspective of their functional significance. Alterations of ICC reported in as well as in GI stromal tumours are reviewed,...
متن کاملImmunomagnetic enrichment of interstitial cells of Cajal.
Disruptions of networks of interstitial cells of Cajal (ICC), gastrointestinal pacemakers and mediators of neurotransmission, can lead to disordered phasic contractions and peristalsis by reducing and uncoupling electrical slow waves. However, detailed analysis of the ICC network behavior has been hampered by their scarcity, limited accessibility in intact tissues, and contamination with other ...
متن کاملInterstitial cells of Cajal in enteric neurotransmission.
Specialised cells known as interstitial cells of Cajal (ICCs), distributed in specific locations within the tunica muscularis of the gastrointestinal tract, serve as electrical pacemakers and mediators of enteric neurotransmission. Until recently, evidence to support a functional role of these cells has been, for the most part, indirect. The role of ICCs in pacemaking or neurotransmission has b...
متن کاملInterstitial cells of Cajal in the urethra
The smooth muscle layer of the urethra generates spontaneous myogenic tone that is thought to make a major contribution to urinary continence. The mechanisms underlying generation of tone remain unclear, however recent studies from our laboratory highlighted a role for a specialised population of pacemaker cells which we originally referred to as interstitial cells (IC) and now term ICC. Urethr...
متن کاملMiniReview Gut Pacemaker Cells : the Interstitial Cells of Cajal ( ICC )
This review will focus on the pacemaker mechanisrns underlying gastrointestinal autonomic rhythmicity in an attempt to elucidate the differences and similarities between the pacemaker mechanisrns in the heart and gut. Interstitial cells of Cajal (ICC) form networks that are widely distributed within the submucosal (ICC-SM) , intra-muscular (ICCIM, ICC-DMP) and inter-muscular layers (ICC-MY) of ...
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ژورنال
عنوان ژورنال: Sultan Qaboos University Medical Journal
سال: 2012
ISSN: 2075-0528
DOI: 10.12816/0003165